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Table 1 Characteristics of patients with ONFH and controls

From: FTO rs62033406 A>G associated with the risk of osteonecrosis of the femoral head among the Chinese Han population

Variable Cases Control p
N 498 498  
Age (year, mean ± SD) 51.77 ± 14.55 50.38 ± 14.52 0.132
  > 51 273 (54.8%) 236 (47.4%)  
  ≤ 51 225 (45.2%) 262 (52.6%)  
Gender    
 Males 280 (56.2%) 311 (62.4%) 0.046
 Females 218 (43.8%) 187 (37.6%)  
Smoking    
 Yes 219 (44.0%) 269 (54.0%) 0.002
 No 279 (56.0%) 229 (46.0%)  
Alcohol consumption    
 Yes 265 (53.2%) 256 (51.4%) 0.568
 No 233 (46.8%) 242 (48.6%)  
Stage    
 III/IV 192 (38.6%)   
 I/II 67 (13.5%)   
 Missing 235 (47.2%)   
RBC (109/L) 3.91 ± 0.83 4.90 ± 0.48  < 0.001
WBC (109/L) 7.67 ± 2.53 5.94 ± 1.59  < 0.001
Hemoglobin (g/L) 118.35 ± 20.11 149.76 ± 17.03  < 0.001
Platelet (109/L) 197.74 ± 72.79 222.23 ± 58.94  < 0.001
Leukocyte (109/L) 1.60 ± 0.65 1.87 ± 0.59  < 0.001
Monocytes (109/L) 0.55 ± 0.26 0.42 ± 0.16  < 0.001
Serum uric acid (μmol/L) 266.67 ± 88.17 322.64 ± 80.7 0.337
Urea (μmol/L) 5.29 ± 5.35 5.06 ± 1.27  < 0.001
Creatinine (μmol/L) 57.32 ± 16.53 67.65 ± 12.57  < 0.001
  1. ONFH, osteonecrosis of the femoral head; RBC, red blood cell; WBC, white blood cell
  2. p values were calculated by χ2 test or Student’s t test
  3. Bold indicate that p < 0.05 indicates statistical significance