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Table 1 Characteristics of patients with ONFH and controls

From: FTO rs62033406 A>G associated with the risk of osteonecrosis of the femoral head among the Chinese Han population

Variable

Cases

Control

p

N

498

498

 

Age (year, mean ± SD)

51.77 ± 14.55

50.38 ± 14.52

0.132

  > 51

273 (54.8%)

236 (47.4%)

 

  ≤ 51

225 (45.2%)

262 (52.6%)

 

Gender

   

 Males

280 (56.2%)

311 (62.4%)

0.046

 Females

218 (43.8%)

187 (37.6%)

 

Smoking

   

 Yes

219 (44.0%)

269 (54.0%)

0.002

 No

279 (56.0%)

229 (46.0%)

 

Alcohol consumption

   

 Yes

265 (53.2%)

256 (51.4%)

0.568

 No

233 (46.8%)

242 (48.6%)

 

Stage

   

 III/IV

192 (38.6%)

  

 I/II

67 (13.5%)

  

 Missing

235 (47.2%)

  

RBC (109/L)

3.91 ± 0.83

4.90 ± 0.48

 < 0.001

WBC (109/L)

7.67 ± 2.53

5.94 ± 1.59

 < 0.001

Hemoglobin (g/L)

118.35 ± 20.11

149.76 ± 17.03

 < 0.001

Platelet (109/L)

197.74 ± 72.79

222.23 ± 58.94

 < 0.001

Leukocyte (109/L)

1.60 ± 0.65

1.87 ± 0.59

 < 0.001

Monocytes (109/L)

0.55 ± 0.26

0.42 ± 0.16

 < 0.001

Serum uric acid (μmol/L)

266.67 ± 88.17

322.64 ± 80.7

0.337

Urea (μmol/L)

5.29 ± 5.35

5.06 ± 1.27

 < 0.001

Creatinine (μmol/L)

57.32 ± 16.53

67.65 ± 12.57

 < 0.001

  1. ONFH, osteonecrosis of the femoral head; RBC, red blood cell; WBC, white blood cell
  2. p values were calculated by χ2 test or Student’s t test
  3. Bold indicate that p < 0.05 indicates statistical significance