Table 5 Haplotype analysis of CYP11B1 polymorphisms and CHD risk
From: Genetic variants in CYP11B1 influence the susceptibility to coronary heart disease
Haplotypes | Frequency in case | Frequency in control | Without adjustment | With adjustment | ||
|---|---|---|---|---|---|---|
OR(95% CI) | p value | OR(95% CI) | p value | |||
Crs4736312Ars5017238Crs5301Grs5283Crs6410Trs4534 | 0.414 | 0.400 | 1.00 | 1.00 | ||
Crs4736312Ars5017238Crs5301Ars5283Crs6410Crs4534 | 0.304 | 0.289 | 1.00 (0.81–1.24) | 0.99 | 1.00 (0.81–1.24) | 1.000 |
Ars4736312Grs5017238Trs5301Grs5283Trs6410Crs4534 | 0.159 | 0.157 | 0.95 (0.74–1.24) | 0.73 | 0.95 (0.73–1.23) | 0.690 |
Crs4736312Ars5017238Crs5301Grs5283Trs6410Crs4534 | 0.107 | 0.144 | 0.72 (0.54–0.96) | 0.027 | 0.72 (0.54–0.96) | 0.024 |