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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Identifying the role of transient receptor potential channels (TRPs) in kidney renal clear cell carcinoma and their potential therapeutic significances using genomic and transcriptome analyses

Fig. 2

Panoramic view of TRP channels in pan-cancer. A The gain frequencies of Copy number variation (CNV) in various cancers. B CNV’s loss frequencies in a variety of cancers. C Pan-cancer-related Single-nucleotide variation (SNV). D TRPs’ survival profiles across cancers. E Variations in TRP mRNA expression across cancers (FC: Fold changes). F The relevant -logP value of each gene's variations across different cancers. G Enrichment analysis for cancer pathway signaling between tumor samples with high- and low-TRPs scores. (NES: normalized enrichment score; The redder the color, the higher the NES; The larger the dot, the lower the corrected p-value). H Relationship between TRPs expression and drug sensitivity based on the GSCA platform in pan-cancer (The darker the red color, the higher the Pearson’s correlation; The larger the dot, the lower the corrected p-value)

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