Table 2 Comparison of cytogenetic profiles of primary infertility cases (male and female) with age and gender matched controls
From: Candidate genes for infertility: an in-silico study based on cytogenetic analysis
Variable | Male primary infertility cases | Age-matched male controls | p-value | Female primary infertility cases | Age-matched female controls | p-value |
|---|---|---|---|---|---|---|
No. of subjects | 66 | 66 | – | 66 | 66 | – |
Age (Mean ± SD) in years | 33.94 ± 6.93 | 34.24 ± 7.23 | 0.8081 | 31.80 ± 6.0 | 33.94 ± 7.28 | 0.0676 |
Mean (%) aberrant metaphases | 26.96 ± 12.52 | 11.31 ± 7.02 | < 0.0001 | 27.22 ± 12.34 | 13.44 ± 7.12 | < 0.0001 |
Mean (%) metaphases with structural aberrations | 16.17 ± 10.74 | 5.29 ± 5.06 | < 0.0001 | 16.74 ± 11.87 | 5.42 ± 4.83 | < 0.0001 |
Mean (%) metaphases with numerical aberrations | 7.24 ± 5.50 | 5.34 ± 4.27 | 0.0284 | 7.4 ± 5.33 | 6.96 ± 4.80 | 0.6191 |
Mean (%) metaphases with both structural and numerical aberrations | 3.25 ± 2.99 | 0.55 ± 1.04 | < 0.0001 | 3.49 ± 2.9 | 1.34 ± 2.15 | < 0.0001 |