Table 3 Comparison of cytogenetic profiles of secondary infertility cases (male and female) with age and gender-matched controls
From: Candidate genes for infertility: an in-silico study based on cytogenetic analysis
Variable | Male secondary infertility cases | Age-matched male controls | p-value | Female secondary infertility cases | Age-matched female controls | p-value |
|---|---|---|---|---|---|---|
No. of subjects | 34 | 34 | – | 35 | 35 | – |
Age (Mean ± SD) in years | 35.91 ± 7.66 | 36.21 ± 8.39 | 0.8781 | 34.06 ± 6.62 | 36.66 ± 7.55 | 0.1302 |
Mean (%) aberrant metaphases | 31.12 ± 14.9 | 11.23 ± 7.88 | < 0.0001 | 32.67 ± 16.24 | 13.91 ± 6.92 | < 0.0001 |
Mean (%) metaphases with structural aberrations | 18.29 ± 11.3 | 5.73 ± 5.99 | < 0.0001 | 20.12 ± 14.01 | 5.06 ± 3.38 | < 0.0001 |
Mean (%) metaphases with numerical aberrations | 8.6 ± 7.4 | 4.29 ± 3.29 | 0.0028 | 7.51 ± 5.39 | 7.16 ± 4.62 | 0.7714 |
Mean (%) metaphases with both structural and numerical aberrations | 4.3 ± 3.4 | 0.68 ± 0.94 | < 0.0001 | 5.38 ± 4.85 | 1.60 ± 2.55 | 0.0001 |