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Table 4 List of chromosomal regions with a significantly higher frequency of structural aberrations in infertile males and females

From: Candidate genes for infertility: an in-silico study based on cytogenetic analysis

Gender

Chromosome/chromosomal arm/chromosomal region

Frequency of aberrations in infertility cases

(Mean ± SD)

Frequency of aberrations in healthy age-matched controls

(Mean ± SD)*

p-value

Male

5q2

1.67 ± 0.58

1.00 ± 0.00

 < 0.0001

 

10q2

1.50 ± 0.71

1.00 ± 0.00

 < 0.0001

 

17q2

1.33 ± 0.58

1.00 ± 0.00

 < 0.0001

Female

6q2

1.17 ± 0.41

1.00 ± 0.00

 < 0.0001

 

16q2

1.50 ± 0.71

1.00 ± 0.00

 < 0.0001

 

Xq2

2.00 ± 1.18

1.00 ± 0.00

 < 0.0001

  1. Significant p-values (<0.05), calculated by t-test, are highlighted in bold
  2. *The zero values were omitted during the calculation of Mean and Standard Deviation due to presence of a high number of zeros in the data
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BMC Medical Genomics

ISSN: 1755-8794

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