Impact of the interaction between the polymorphisms and hypermethylation of the CD36 gene on a new biomarker of type 2 diabetes mellitus: circulating soluble CD36 (sCD36) in Senegalese females

Table 2 Clinical and biochemical characteristics of study participants according to groups

Variables	Control n = 50	T2DM n = 50	p value
Mean age (years)	48.98 ± 7.52	50.80 ± 5.93	0.18
Diabetes duration (years)	–	8.89 ± 6.20	–
Waist–hip ratio	0.83 ± 0.09	0.88 ± 0.07	< 0.0001***
Height (cm)	166.50 ± 6.64	164.32 ± 6.75	0.11
Weight (kg)	67.63 ± 9.87	66.26 ± 8.03	0.45
Body mass index (kg/m²)	24.25 ± 2.75	24.48 ± 2.33	0.66
Fasting blood glucose (g/l)	0.86 ± 0.13	1.77 ± 0.90	< 0.0001***
Glycated hemoglobin (%)	5.00 ± 0.49	9.32 ± 2.27	< 0.0001***
Insulin (µUI/ml)	17.73 ± 6.37	29.00 ± 15.62	0.01**
IR-HOMA	3.80 ± 1.67	11.82 ± 13.09	0.003**
Total cholesterol (g/l)	2.13 ± 0.44	2.28 ± 0.50	0.12
HDL Cholesterol (g/l)	0.62 ± 0.14	0.56 ± 0.18	0.08
LDL Cholesterol (g/l)	1.40 ± 0.37	1.65 ± 0.53	0.007**
Triglycerides (g/l)	0.80 ± 0.31	0.94 ± 0.55	0.13

HOMA-IR Homeostasis Model Assessment-Insulin Resistance, T2DM Type 2 Diabetes mellitus, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.0001

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