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Table 6 Comparison of baseline population characteristics between groups by genetic variants at  CD36 gene

From: Impact of the interaction between the polymorphisms and hypermethylation of the CD36 gene on a new biomarker of type 2 diabetes mellitus: circulating soluble CD36 (sCD36) in Senegalese females

 

GG

AA/AG

Control

T2DM

p value

Control

T2DM

p value

rs1761667

      

Waist–hip ratio

0.82 ± 0.10

0.88 ± 0.07

0.02*

0.83 ± 0.07

0.89 ± 0.06

0.008**

Body mass index (kg/m2)

24.75 ± 2.61

24.30 ± 1.97

0.50

23.99 ± 3.13

24.66 ± 2.50

0.40

Total cholesterol (g/l)

2.23 ± 0.42

2.28 ± 0.42

0.72

2.04 ± 0.45

2.29 ± 0.58

0.10

HDL cholesterol (g/l)

0.63 ± 0.13

0.59 ± 0.17

0.28

0.61 ± 0.15

0.54 ± 0.18

0.17

LDL cholesterol (g/l)

1.46 ± 0.30

1.62 ± 0.47

0.18

1.34 ± 0.41

1.69 ± 0.59

0.02*

Triglycerides (g/l)

0.84 ± 0.35

0.95 ± 0.63

0.47

0.76 ± 0.28

0.92 ± 0.48

0.13

 

CC

AA/AC

Control

T2DM

p value

Control

T2DM

p value

rs3211867

      

Waist–hip ratio

0.80 ± 0.07

0.90 ± 0.08

 < 0.0001***

0.84 ± 0.09

0.87 ± 0.06

0.11

Body mass index (kg/m2)

23.46 ± 2.86

24.47 ± 2.34

0.24

24.90 ± 2.80

24.49 ± 2.20

0.52

Total cholesterol (g/l)

2.11 ± 0.48

2.33 ± 0.60

0.22

2.15 ± 0.43

2.25 ± 0.42

0.33

HDL cholesterol (g/l)

0.59 ± 0.15

0.55 ± 0.13

0.39

0.64 ± 0.13

0.57 ± 0.20

0.15

LDL cholesterol (g/l)

1.45 ± 0.37

1.72 ± 0.66

0.11

1.37 ± 0.37

1.61 ± 0.43

0.02*

Triglycerides (g/l)

0.73 ± 0.25

1.07 ± 0.68

0.04*

0.84 ± 0.34

0.85 ± 0.44

0.94

  1. HOMA-IR Homeostasis Model Assessment-Insulin Resistance, T2DM Type 2 Diabetes Mellitus, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.0001