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Table 8 Effects of the CD36 gene methylation on clinical and biological parameters

From: Impact of the interaction between the polymorphisms and hypermethylation of the CD36 gene on a new biomarker of type 2 diabetes mellitus: circulating soluble CD36 (sCD36) in Senegalese females

Variables

Control

Type 2 Diabetes Mellitus

Unmethylated

Methylated

p value

Unmethylated

Methylated

p value

Body mass index (kg/m2)

24.55 ± 2.84

23.81 ± 3.05

0.54

24.53 ± 2.33

24.41 ± 2.15

0.86

Waist–hip ratio

0.82 ± 0.08

0.83 ± 0.10

0.87

0.88 ± 0.06

0.88 ± 0.07

0.78

Glycated hemoglobin (%)

4.89 ± 0.99

4.55 ± 1.38

0.37

9.05 ± 3.00

9.34 ± 2.06

0.96

IR-HOMA

3.81 ± 1.83

3.19 ± 1.71

0.39

12.89 ± 16.78

9.37 ± 5.22

0.31

Total cholesterol (g/l)

2.09 ± 0.45

2.26 ± 0.41

0.20

2.37 ± 0.58

2.18 ± 0.35

0.15

HDL cholesterol (g/l)

0.61 ± 0.14

0.64 ± 0.13

0.63

0.55 ± 0.13

0.58 ± 0.23

0.52

LDL cholesterol (g/l)

1.36 ± 0.37

1.52 ± 0.34

0.17

1.76 ± 0.58

1.52 ± 0.43

0.10

Triglycerides (g/l)

0.85 ± 0.32

0.66 ± 0.25

0.04*

0.89 ± 0.49

1.00 ± 0.63

0.51

  1. HOMA-IR Homeostasis Model Assessment-Insulin Resistance, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.0001
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BMC Medical Genomics

ISSN: 1755-8794

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