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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Comprehensive analysis reveals the potential value of inflammatory response genes in the prognosis, immunity, and drug sensitivity of lung adenocarcinoma

Fig. 5

Multidimensional features of IRGS-S genes in LUAD. A The difference of mRNA expression levels of 8 IRGS-S genes between LUAD normal and tumor samples. B The bar graph showing the CNV gain/loss frequency of 8 IRGS-S genes. C The CNV alteration positions of these 8 IRGS-S genes on the human chromosome. D The waterfall plot reflecting the frequency of genetic alteration in these 8 IRGS-S genes in LUAD. E The plot reflecting the interrelationship between immune cells, IRGS-S genes, and IRGS. F Network map intuitively shows the correlation between FDA approved drugs and 8 IRGS-S genes. PSEN1 and CD69 associated with 42 and 41 drugs, respectively, with the highest proportion. The size of nodes indicates the correlation degree (number); purple lines represent positive correlation and orange represents negative correlation. The thickness of the lines represents the correlation degree (cor). G Docking pose and interaction of Tyrothricin with TNFSF9. H Docking pose and interaction of Fluphenazine with CD69

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BMC Medical Genomics

ISSN: 1755-8794

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