Skip to main content

Table 3 Summary statistics of bone marrow plasma cell infiltration grouped by method and number of mutations

From: Correlation of plasma cell assessment by phenotypic methods and molecular profiles by NGS in patients with plasma cell dyscrasias

Mutation load/type

PCD type

Disease relapse/progression

Serum light chains mean mg/L, range

M-gradient mean g/L, range

β2, mean mg/L, range

No mutation

N = 26

MGUS = 5

ALA = 3

MM = 17

7/26 (27%)

611 (14.3–2830)

13 (3–60.0)

4.2 (0.32–17.42)

1 mutation

N = 41

MGUS = 2

ALA = 1

IP = 1

MM = 37

15/41–37%

737 (11.0–8320)

30 (4.8–72.4)

4.6 (1.55–16.7)

 > 1 mutation

N = 23

MM = 23

15/23–65%

1773 (6.2–25,000)

49 (3.70–367.0)

6.7(1.8–37)