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Fig. 2 | BMC Medical Genomics

Fig. 2

From: TMBur: a distributable tumor mutation burden approach for whole genome sequencing

Fig. 2

Predictive value of TMB estimates on ICI response. A Tumor types represented in the cohort, and genomic SNV TMB estimates per sample. B Spearman correlation between TMB estimates derived from different genomic subsets. C Time to progression in patients with a high (≥ 10) or low (< 10) TMB. p Values were determined using a log-rank test. In all panels, SNV counts describe TMB derived using SNVs only, and total counts refer to SNV and indels. TMB estimates are as described in Methods. Patients at risk for progression at each time point are shown in the tables below

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