Selective gene expression profiling contributes to a better understanding of the molecular pathways underlying the histological changes observed after RHMVL

Table 1 List of selected marker genes*

Mechanisms	Pathways	Genes	References (e.g.)
Vasoactive pathways	NO pathway	eNOS, iNOS, nNOS, Gucy1a2	[22], [28], [35]
	Arachidonic acid pathway	PLA2G4A, COX1, COX2, PGIS, TXS, Tbxa2r	[27], [36]
	Endothelin pathway	Edn1, ET-R_A, ET-R_B	[27], [36], [37]
	Hepatic arterial buffer response”	Adora1, Adora2a, Adora3	[20], [23]
Vascular remodeling		CAV1, Icam1, Pecam1 Prdx1, vWF, Lamc2, Vegfa, Vegfb	[24], [37,38,39]
Liver regeneration	Liver cell proliferation	PCNA, Tyms	[40], [41]
	Liver cell growth factors	Egf, Egfr, Egr1, Hgf, Met	[19], [21, 25]
	Cytokines	IL10, IL1b, IL6, Mif, Tgfb1, Tnf	[22], [25], [36], [37]

^*List of selected marker genes for each mechanism and pathway based on selected references

ISSN: 1755-8794