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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Identification of core genes and pathways between geriatric multimorbidity and renal insufficiency: potential therapeutic agents discovered using bioinformatics analysis

Fig. 1

Summary of the whole study design. Text mining procedures were conducted using Pubmed2Ensembl to identify genes related to Geriatric Multimorbidity (G-M) and Renal insufficiency. Genes collection enrichment was used GeneCodis to find genes enriched in the GO biological process terms and KEGG pathways. STRING and CytoHubba were used to construct a protein–protein interaction network and screen the proteins encoded by the hub genes according to the degree of the nodes. MCODE were used to identify the related protein network modules and calculate the score of each module. DAVID and ClueGO were used to analyze the GO biological process terms and KEGG pathways. DGIDB was used to classify potential drug targets based on the lists of significant genes. KEGG: Kyoto Encyclopedia of Genes and Genomes

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BMC Medical Genomics

ISSN: 1755-8794

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