Fig. 4

Weighted gene co-expression network analysis (WGCNA). (a) Soft threshold determination in GSE100927 (CAS dataset). (b) Soft threshold determination in GSE10334 (PD dataset). (c) Hierarchical clustering dendrograms of the top 5000 genes with the highest standard deviation in the CAS clustered based on a dissimilarity measure (1-TOM). (d) Hierarchical clustering dendrograms of the top 5000 genes with the highest standard deviation in the PD clustered based on a dissimilarity measure (1‐TOM). (e) Module–trait relationships in CAS. Each different colored module contains the corresponding correlation and p-value. (f) Module–trait relationships in PD. Each different colored module contains the corresponding correlation and p-value