Table 1 Univariate and multivariate logistic regression of factors influencing TMB-high in cervical cancer
Factor | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (95%CI) | p value | OR (95%CI) | p value | |
Histological subtypes (scc, non-scc) | 5.358(1.837–15.623) | 0.002 | 4.767(0.992–22.902) | 0.051 |
KMT2C (mutant, wild) | 11.368(3.744–34.520) | < 0.001 | 13.160(2.814–61.553) | 0.001 |
LRP1B (mutant, wild) | 3.240(0.995–10.553) | 0.051 | 5.981(1.311–27.291) | 0.021 |
PIK3CA (mutant, wild) | 2.657(1.149–6.148) | 0.022 | 1.208(0.359–4.062) | 0.760 |
FBXW7 (mutant, wild) | 11.196(2.322–53.983) | 0.003 | 5.338(0.819–34.764) | 0.080 |
PRKDC (mutant, wild) | 6.234(1.221–31.820) | 0.028 | 1.966(0.240–16.122) | 0.529 |
KMT2D (mutant, wild) | 6.367(2.320–17.473) | < 0.001 | 2.520(0.663–9.574) | 0.175 |
EP300(mutant, wild) | 6.234(1.221–31.820) | 0.028 | 7.876(0.997–62.241) | 0.050 |