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Table 6 Relationships of DIO3 and THRB ΔCT with BMI, weight and central obesity of study participants*

From: Alterations of DNA methylation and expression of genes related to thyroid hormone metabolism in colon epithelium of obese patients

 

DIO3 ΔCT

THRB ΔCT

βC

P valueA

βC

P valueB

BMI

    

Crude

− 0.365

0.022

0.382

0.017

Adjusted

− 0.315

0.050

0.302

0.054

Weight

    

Crude

− 0.323

0.045

0.371

0.020

Adjusted

− 0.300

0.061

0.307

0.056

Central obesity

    

Crude

− 0.300

0.063

0.260

0.110

Adjusted

− 0.247

0.143

0.213

0.200

  1. Multiple linear regression and simple linear regression were used to study the linear relationship between variables
  2. AAdjusted for red meat consumption and smoking
  3. BAdjusted for NSAID use, consumption of vitamin D and colon cancer family history
  4. Cβ refers to the standardized coefficient
  5. −Confounders with P < 0.2 included in the adjusted analysis
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BMC Medical Genomics

ISSN: 1755-8794

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