Fig. 1
From: Genes related to allergen exposure in allergic rhinitis: a gene-chip-based study in a mouse model
Effect of allergen exposure on allergic symptoms and immune responses in OVA-induced AR mice. A Nasal symptoms. B Serum OVA-specific IgE. C, D Representative images of neutrophils (C) and eosinophils (D) infiltrations in nasal mucosa and quantitative analysis (magnification, 400X); positive cells are indicated by arrows and scale bars are 20 μm for neutrophils and 10 μm for eosinophils. Control: sensitized and challenged with saline and euthanized 2 h after the last challenge; OVA: sensitized and challenged with OVA and euthanized 2 h after the last challenge; 4w-after: sensitized and challenged with OVA and euthanized 4w-after the last challenge. Data are expressed as the mean ± SD (n = 6 in each group). Results are representative of two independent experiments with similar results. *P < 0.05; **P < 0.01; ***P < 0.001