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Table 2 Validation of the top 21 DEG identified by gene co-expression analysis by real-time PCR

From: Genes related to allergen exposure in allergic rhinitis: a gene-chip-based study in a mouse model

Genes

2−△△ct(control)

2−△△ct(OVA)

2−△△ct(4w-after)

BCL3

1.45 ± 0.8

9.43 ± 0.87**

1.77 ± 0.28##

CSF2RB2

2.32 ± 2.3

18.04 ± 8.73*

3.4 ± 1.76#

HNRNPA3

1.18 ± 0.46

0.58 ± 0.07

0.85 ± 0.06##

SBNO2

1.38 ± 0.45

2.93 ± 0.55*

0.74 ± 0.22##

NFKB2

0.65 ± 0.32

2.17 ± 0.69*

0.51 ± 0.06#

FABP5

0.99 ± 0.14

4.18 ± 1.89*

2.16 ± 2.28

SLC6A14

0.81 ± 0.17

1.66 ± 0.09**

0.65 ± 0.08##

SPRR2A1

2.26 ± 1.65

5.16 ± 4.28

6.09 ± 8.1

CISH

0.87 ± 0.14

3.71 ± 0.78**

1.16 ± 0.56#

MS4A6D

0.62 ± 0.33

2.75 ± 0.99*

0.84 ± 0.25#

SOCS3

2.91 ± 3.35

15.8 ± 5.74*

4.25 ± 2.72#

CD53

0.85 ± 0.17

2.17 ± 0.48*

1.08 ± 0.37#

ENTPD3

1.68 ± 1.1

5.12 ± 1.17*

2.82 ± 0.56#

BHLHE40

3.34 ± 2.31

9.27 ± 1.94*

4.2 ± 0.88#

CLDN4

1.17 ± 0.85

3.34 ± 1.03*

1.07 ± 0.63#

OSMR

1.38 ± 0.45

2.93 ± 0.55*

0.74 ± 0.22##

TNFAIP2

0.70 ± 0.47

3.83 ± 1.61*

0.87 ± 0.42#

TNIP3

2.35 ± 1.19

14.28 ± 2.83**

2.25 ± 1.89##

TREM1

0.65 ± 0.38

1.82 ± 0.43**

0.51 ± 0.16##

ZC3H12A

1.03 ± 0.27

9.34 ± 1.78**

1.68 ± 0.33##

RPL38

0.89 ± 0.13

0.58 ± 0.39

3.24 ± 0.58##

  1. The unpaired Student's t test was used to analyze gene expression.* P < 0.05,** P < 0.01, compared to control group; # P < 0.05,## P < 0.01, compared to OVA group