Table 4 Association between CYP4V2 rs1398007 and IS patients with and without hypertension
Model | Genotype | Control | IS with HYP | IS without HYP | IS patients with HYP vs. controls | IS patients without HYP vs. controls | IS patients with HYP vs. without HYP | |||
|---|---|---|---|---|---|---|---|---|---|---|
Codominant | C/C | 272 (47.3%) | 155 (39.1%) | 87 (48.6%) | 1 | 0.008 | 1 | 0.031 | 1 | 0.035 |
T/C | 250 (43.5%) | 212 (53.5%) | 86 (48%) | 1.50 (1.14–1.96) | 1.05 (0.74–1.48) | 1.41 (0.98–2.03) | ||||
T/T | 53 (9.2%) | 29 (7.3%) | 6 (3.4%) | 0.97 (0.59–1.59) | 0.37 (0.15–0.88) | 2.63 (1.05–6.61) | ||||
Dominant | C/C | 272 (47.3%) | 155 (39.1%) | 87 (48.6%) | 1 | 0.010 | 1 | 0.680 | 1 | 0.030 |
T/C-T/T | 303 (52.7%) | 241 (60.9%) | 92 (51.4%) | 1.40 (1.08–1.82) | 0.93 (0.66–1.31) | 1.49 (1.04–2.13) | ||||
Log-additive | – | – | – | – | 1.18 (0.96–1.44) | 0.120 | 0.83 (0.63–1.09) | 0.170 | 1.48 (1.09–2.02) | 0.011 |