CYP4 subfamily V member 2 (CYP4V2) polymorphisms were associated with ischemic stroke in Chinese Han population

BMC Medical Genomics

Table 6 MDR analysis for SNP–SNP interaction in CYP4V2 with IS susceptibility

Model	Training bal. acc.	Testing bal. acc.	CVC	OR (95% CI)	p
rs1398007	0.5417	0.5417	10/10	1.40 (1.11–1.76)	0.0046
rs13146272, rs3736455	0.5503	0.5139	5/10	1.71 (1.29–2.25)	0.0001
rs1398007, rs3736455, rs1053094	0.5638	0.5104	7/10	1.65 (1.31–2.09)	< 0.0001
rs1398007, rs13146272, rs3736455, rs1053094	0.5818	0.5130	10/10	1.96 (1.54–2.49)	< 0.0001
rs1398007, rs13146272, rs3736455, rs1053094, rs56413992	0.5940	0.5000	10/10	2.07 (1.63–2.63)	< 0.0001

MDR, multifactor dimensionality reduction; SNP, single nucleotide polymorphism; Bal. Acc., balanced accuracy; CVC, cross–validation consistency; OR, odds ratio; CI, confidence interval
p values were calculated using χ² tests
Bold indicate that p < 0.05 indicates statistical significance

ISSN: 1755-8794