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Table 2 Basic information and allele frequencies of rs738409, rs3747207, rs4823173, and rs2896019 in PNPLA3

From: Contribution of PNPLA3 gene polymorphisms to hepatocellular carcinoma susceptibility in the Chinese Han population

SNP_ID

Gene

Chr

Base pair

Allele

MAF

HWE

OR (95% CI)

χ2

p

FDR-p

Case

Control

p-value

rs738409

PNPLA3

22

43,928,847

C > G

0.422

0.378

0.209

1.21 (1.00–1.45)

4.029

0.045

0.060

rs3747207

PNPLA3

22

43,928,975

G > A

0.415

0.374

0.066

1.19 (0.99–1.43)

3.513

0.061

0.061

rs4823173

PNPLA3

22

43,932,850

G > A

0.420

0.367

0.095

1.25 (1.04–1.50)

5.693

0.017

0.068

rs2896019

PNPLA3

22

43,937,814

T > G

0.423

0.371

0.207

1.25 (1.04–1.50)

5.640

0.018

0.035

  1. SNP single nucleotide polymorphism; Chr chromosome; MAF minor allele frequency; HWE Hardy–Weinberg equilibrium; OR odds ratio; 95% CI 95% confidence interval; χ2 chi-square; FDR false discovery rate
  2. Bold values indicate statistical significance
  3. p-value was calculated by χ2 test