SNP_ID | Genotype | Crude OR (95% CI) | p | Statistical power | Prior probability | ||||
---|---|---|---|---|---|---|---|---|---|
0.25 | 0.1 | 0.01 | 0.001 | 0.0001 | |||||
rs738409 | Overall analysis | ||||||||
G versus C | 1.21(1.00–1.45) | 0.039 | 0.990 | 0.106 | 0.261 | 0.796 | 0.975 | 0.997 | |
GG versus CC | 1.49(1.00–2.22) | 0.045 | 0.500 | 0.213 | 0.448 | 0.899 | 0.989 | 0.999 | |
Log-additive | 1.22(1.01–1.48) | 0.044 | 0.982 | 0.118 | 0.286 | 0.815 | 0.978 | 0.998 | |
Age > 55 | |||||||||
CG versus CC | 1.53(1.01–2.32) | 0.045 | 0.163 | 0.227 | 0.468 | 0.906 | 0.990 | 0.999 | |
CG + GG versus CC | 1.55(1.04–2.30) | 0.030 | 0.435 | 0.169 | 0.379 | 0.870 | 0.985 | 0.999 | |
Log-additive | 1.33(1.00–1.76) | 0.046 | 0.800 | 0.147 | 0.341 | 0.851 | 0.983 | 0.998 | |
rs3747207 | Age > 55 | ||||||||
GA versus GG | 1.57(1.04–2.37) | 0.032 | 0.414 | 0.187 | 0.409 | 0.884 | 0.987 | 0.999 | |
GA + AA versus GG | 1.55(1.05–2.30) | 0.030 | 0.435 | 0.169 | 0.379 | 0.870 | 0.985 | 0.999 | |
rs4823173 | Overall analysis | ||||||||
A versus G | 1.25(1.04–1.50) | 0.016 | 0.975 | 0.048 | 0.132 | 0.625 | 0.944 | 0.994 | |
AA versus GG | 1.63(1.08–2.46) | 0.020 | 0.346 | 0.148 | 0.342 | 0.851 | 0.983 | 0.998 | |
GA + AA versus GG | 1.35(1.04–1.77) | 0.030 | 0.777 | 0.103 | 0.257 | 0.792 | 0.975 | 0.997 | |
Log-additive | 1.28(1.06–1.55) | 0.011 | 0.948 | 0.035 | 0.098 | 0.545 | 0.924 | 0.992 | |
Age > 55 | |||||||||
GA versus GG | 1.62(1.07–2.45) | 0.022 | 0.358 | 0.157 | 0.359 | 0.860 | 0.984 | 0.998 | |
GA + AA versus GG | 1.62(1.09–2.40) | 0.016 | 0.351 | 0.121 | 0.293 | 0.820 | 0.979 | 0.998 | |
Log-additive | 1.36(1.02–1.82) | 0.039 | 0.745 | 0.134 | 0.318 | 0.837 | 0.981 | 0.998 | |
rs2896019 | overall analysis | ||||||||
G versus T | 1.25(1.04–1.50) | 0.016 | 0.975 | 0.048 | 0.132 | 0.625 | 0.944 | 0.994 | |
TG versus TT | 1.33(1.01–1.76) | 0.012 | 0.856 | 0.039 | 0.109 | 0.574 | 0.932 | 0.993 | |
GG versus TT | 1.59(1.06–2.39) | 0.026 | 0.390 | 0.165 | 0.373 | 0.867 | 0.985 | 0.998 | |
TG + GG versus TT | 1.38(1.06–1.81) | 0.020 | 0.727 | 0.076 | 0.198 | 0.731 | 0.965 | 0.996 | |
Log-additive | 1.28(1.06–1.55) | 0.011 | 0.948 | 0.035 | 0.098 | 0.545 | 0.924 | 0.992 | |
Age > 55 | |||||||||
TG versus TT | 1.78(1.17–2.70) | 0.007 | 0.210 | 0.087 | 0.222 | 0.759 | 0.969 | 0.997 | |
TG + GG versus TT | 1.75(1.18–2.61) | 0.006 | 0.225 | 0.075 | 0.195 | 0.728 | 0.964 | 0.996 | |
Log-additive | 1.40(1.05–1.86) | 0.020 | 0.683 | 0.082 | 0.211 | 0.746 | 0.967 | 0.997 |