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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Diagnostic and therapeutic challenges of glioblastoma as an initial malignancy of constitutional mismatch repair deficiency (CMMRD): two case reports and a literature review

Fig. 2

MRI of Patient 1 at onset showed a left frontal tumor. a The tumor was heterogeneously enhanced with gadolinium on T1WI. b FLAIR showed peritumoral edema. MRI c, d revealed that another non-enhancing tumor developed at the right temporal lobe. The tumor was hyper-intense on FLAIR d and was not enhancing with gadolinium on T1WI c. MRI e, f demonstrating a tumor at the left operculum. The tumor was enhanced with gadolinium on T1WI e and showed hyperintensity on FLAIR f. g Hematoxylin–eosin (HE) staining of a specimen from the 1st surgery for left frontal tumor showed a glioblastoma. (OLYMPUS BX43/ × 20 0.50FN 26.5, Nikon DIGITAL SIGHT DS-Fi2 Microscope C-mount Camera System, NIS ELEMENTS, resolution: 1280 × 960)

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BMC Medical Genomics

ISSN: 1755-8794

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