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Fig. 4 | BMC Medical Genomics

Fig. 4

From: The role of Neanderthal introgression in liver cancer

Fig. 4

Gene expression is similar in samples with Neanderthal introgression and without Neanderthal introgression. Expression in counts per million (CPM) for genes with either A–D a significant enrichment of somatic mutation on introgressed haplotypes compared to modern haplotypes and a significant difference in expression of Neanderthal allele in tumor compared to unaffected liver prior to p-value adjustment, or E–H a significant difference in expression of Neanderthal allele in tumor compared to unaffected liver after p-value adjustment. For each gene, and each data set, we performed a Wilcoxon rank sum test between samples with introgression (Neanderthal, dark blue) and without (Modern; light blue). p-values were annotated for each comparison: ns p > 0.05, * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001

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