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Table 1 Baseline characteristics of study participants categorized according to the Cav-1 genotypes in obese and overweight women (n = 386)

From: Interaction between caveolin-1 polymorphism and dietary fat quality indexes on visceral adiposity index (VAI) and body adiposity index (BAI) among overweight and obese women: a cross-sectional study

Variables

CAV-1 genotypes

GG (N = 193)

AG (N = 90)

AA (N = 101)

P value

P value*

Mean ± SD

Demographic characteristics

 Age (year)

37.56 ± 9.49

35.85 ± 8.91

35.67 ± 8.71

0.15

0.33

 Onset of obesity (year)

23.04 ± 10.02

23.76 ± 9.04

22.59 ± 8.41

0.72

0.19

 Physical activity (MET/h)

1215.46 ± 2033.81

1379.12 ± 2823.33

1073.74 ± 1761.48

0.74

0.77

Anthropometric measurements

 Weight (kg)

79.71 ± 10.91

81.10 ± 12.24

83.01 ± 14.05

0.08

0.38

 Height (cm)

161.30 ± 6.08

161.27 ± 5.34

160.68 ± 5.80

0.66

0.80

 WC (cm)

96.61 ± 15.20

95.57 ± 18.23

100.26 ± 12.01

0.16

0.25

 HC (cm)

113.59 ± 9.49

111.44 ± 6.76

116.10 ± 11.07

0.09

0.07

 BMI (kg/m2)

30.68 ± 4.02

31.06 ± 4.06

32.19 ± 4.75

0.01

0.07

 WHR

0.93 ± 0.05b

1.94 ± 9.59b

0.94 ± 0.05

0.19

0.06

 BAI

29.35 ± 7.94

28.57 ± 8.72a

30.96 ± 5.80a

0.18

0.06

 VAI

2.13 ± 1.24 b

3.27 ± 3.47b

2.62 ± 2.05

0.006

0.006

Blood pressure

 SBP (mm Hg)

109.60 ± 15.05

113.05 ± 17.98

112.79 ± 12.04

0.19

0.78

 DBP (mm Hg)

75.87 ± 10.77

79.45 ± 11.63

79.22 ± 8.85

0.02

0.47

Biochemical variables

 FBS (mg/dL)

87.98 ± 9.62

87 ± 11.39

86.91 ± 8.46

0.70

0.74

 TC (mg/dL)

186.76 ± 33.74

187.58 ± 44.95

179.21 ± 30.67

0.29

0.27

 TG (mg/dL)

113.11 ± 51.20

126.77 ± 61.42

123.90 ± 70.50

0.28

0.21

 HDL (mg/dL)

49.07 ± 11.16b

42.84 ± 11.39b

44.90 ± 9.17

0.001

0.03

 LDL (mg/dL)

98.88 ± 22.66

89.49 ± 26.45

92.54 ± 24.13

0.03

0.08

 GOT (U/L)

18.27 ± 7.44

17.96 ± 7.03

17.95 ± 9.13

0.95

0.53

 GPT (U/L)

19.04 ± 13.95

19.35 ± 11.66

20.71 ± 15.81

0.71

0.61

Supplements intake

   

0.18

0.83

 Yes

87 (57.6%)

27 (17.9%)

37 (24.5%)

  

 No

83 (47.7%)

42 (24.1%)

49 (28.2%)

  

Marital status

   

0.98

0.20

 Single

55 (51.4)

24 (22.4)

28 (26.2)

  

 Married

137 (50.6)

63 (23.2)

71 (26.2)

  

Education status

   

0.17

0.009

 Illiterate

1 (25)

2 (50)

1 (25)

  

 Under diploma

20 (41.7)

12 (25)

16 (33.3)

  

 Diploma

68 (46.6)

33 (22.6)

45 (30.8)

  

 Bachelor and higher than

103 (57.2)

40 (22.2)

37 (20.6)

  

Economic status

   

0.20

0.23

 Poor

39 (45.3)

19 (22.1)

28 (32.6)

  

 Moderate

83 (47.4)

46 (26.3)

46 (26.3)

  

 Good

62 (59)

19 (18.1)

24 (22.9)

  

Family history of obesity

   

0.55

0.15

 Yes

129 (51.2)

56 (22.2)

67 (26.6)

  

 No

48 (45.3)

28 (26.4)

30 (28.3)

  
  1. SD standard deviation, IPAQ International Physical Activity Questionnaire, WC waist circumference, BAI body adiposity index, VAI visceral adiposity index, SBP systolic blood pressure, DBP diastolic blood pressure, TG triglyceride, HDL high density lipoprotein, LDL low density lipoprotein, GOT glutamic oxaloacetic transaminase, GPT glutamate pyruvate transaminase, BMI body mass index, HC hip circumference, WHR waist-to-hip ratio, TC total cholesterol
  2. Values are represented as means ± SD. BMI is collinear
  3. Categorical variables: N (%)
  4. Independent T test (P value) was performed to identify significant differences between Cav-1 genotypes in crude model
  5. ANCOVA (P value*) was performed to adjusted potential confounding factors (age, energy intake, Physical activity, BMI)
  6. BMI consider as collinear variable for anthropometrics and body composition variables, these variables control with energy intake, age and, physical activity
  7. Bold indicate p values < 0.05 were considered as significant, and p values = 0.06 were considered as marginally significant
  8. aThe significant difference was seen between AA and AG
  9. bThe significant difference was seen between GG and AG
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BMC Medical Genomics

ISSN: 1755-8794

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