Table 3 Logistic regression analyses of associations between PPARγ rs1801282 C > G, rs3856806 C > T, PPARGC1A rs8192678 C > T, rs2970847 C > T, PPARGC1B rs7732671 G > C, rs17572019 G > A polymorphisms and risk of GC

PPARγ rs1801282 C > G

CC

452

92.24

1317

89.23

1

GC

34

6.94

151

10.23

0.66 (0.45–0.97)

0.033

0.62 (0.42–0.93)

0.019

GG

1

0.2

4

0.27

0.73 (0.08–6.53)

0.777

0.83 (0.08–8.25)

0.874

GC + GG

35

7.14

155

10.5

0.66 (0.45–0.96)

0.032

0.63 (0.42–0.93)

0.019

CC + GC

486

99.18

1468

99.46

1

GG

1

0.2

4

0.27

0.76 (0.08–6.77)

0.802

0.86 (0.09–8.59)

0.9

G allele

36

3.67

159

5.39

PPARγ rs3856806 C > T

CC

278

56.73

868

58.81

1

CT

188

38.37

544

36.86

1.08 (0.87–1.34)

0.486

1.08 (0.87–1.35)

0.482

TT

21

4.29

60

4.07

1.09 (0.65–1.83)

0.736

1.02 (0.60–1.74)

0.931

CT + TT

209

42.65

604

40.92

1.08 (0.88–1.33)

0.465

1.08 (0.87–1.33)

0.501

CC + CT

466

95.1

1412

95.66

1

TT

21

4.29

60

4.07

1.06 (0.64–1.76)

0.818

0.99 (0.59–1.68)

0.977

T allele

230

23.47

664

22.49

PPARGC1A rs8192678 C > T

CC

169

34.49

454

30.76

1

CT

236

48.16

726

49.19

0.87 (0.69–1.10)

0.248

0.89 (0.70–1.13)

0.346

TT

82

16.73

292

19.78

0.75 (0.56–1.02)

0.067

0.78 (0.57–1.07)

0.121

CT + TT

318

64.9

1018

68.97

0.84 (0.68–1.04)

0.113

0.86 (0.69–1.08)

0.189

CC + CT

405

82.65

1180

79.95

1

TT

82

16.73

292

19.78

0.82 (0.63–1.07)

0.145

0.84 (0.63–1.11)

0.209

T allele

400

40.82

1310

44.38

PPARGC1Ars2970847 C > T

CC

303

61.84

890

60.3

1

CT

160

32.65

515

34.89

0.91 (0.73–1.14)

0.415

0.90 (0.72–1.14)

0.384

TT

24

4.9

67

4.54

1.05 (0.65–1.71)

0.837

1.16 (0.70–1.91)

0.567

CT + TT

184

37.55

582

39.43

0.93 (0.75–1.15)

0.491

0.93 (0.75–1.16)

0.521

CC + CT

463

94.49

1405

95.19

1

TT

24

4.9

67

4.54

1.09 (0.67–1.75)

0.732

1.20 (0.73–1.97)

0.471

T allele

208

21.22

649

21.99

PPARGC1B rs7732671 G > C

GG

436

88.98

1299

88.01

1

GC

50

10.2

166

11.25

0.90 (0.64–1.25)

0.526

0.96 (0.68–1.36)

0.821

CC

1

0.2

7

0.47

0.43 (0.05–3.47)

0.425

0.42 (0.05–3.47)

0.42

GC + CC

51

10.41

173

11.72

0.88 (0.63–1.22)

0.442

0.94 (0.67–1.32)

0.708

GG + GC

486

99.18

1465

99.25

1

CC

1

0.2

7

0.47

0.43 (0.05–3.51)

0.431

0.42 (0.05–3.48)

0.423

 C allele

52

5.31

180

6.1

PPARGC1B rs17572019 G > A

GG

435

88.78

1298

87.94

1

GA

50

10.2

165

11.18

0.90 (0.65–1.26)

0.555

0.98 (0.70–1.39)

0.916

AA

1

0.2

9

0.61

0.33 (0.04–2.63)

0.296

0.27 (0.03–2.21)

0.224

GA + AA

51

10.41

174

11.79

0.88 (0.63–1.22)

0.427

0.94 (0.67–1.32)

0.706

GG + GA

485

98.98

1463

99.12

1

AA

1

0.2

9

0.61

0.34 (0.04–2.65)

0.3

0.27 (0.03–2.22)

0.224

 A allele

52

5.31

183

6.2