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Fig. 3 | BMC Medical Genomics

Fig. 3

From: A novel homozygous TUB mutation associated with autosomal recessive retinitis pigmentosa in a consanguineous Chinese family

Fig. 3

Hydrophobicity analysis of the wild and mutant proteins, multiple alignment of the amino acid sequences around Asn460 in different species, and predicted model structures of the human TUB protein. A Hydrophobicity analysis performed by Novopro, indicating a slight decrease in hydrophilicity caused by the variant. B Multiple-sequence alignments of TUB around Asn460 among different species, indicating that this variant was highly conserved among species. C Predicted structures of the human TUB protein (residues 289 through 561) using PyMOL. The p.Asn460Ser variant in TUB is indicated with ball-and-stick models. N, asparagine; S, serine

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BMC Medical Genomics

ISSN: 1755-8794

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