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Fig. 6 | BMC Medical Genomics

Fig. 6

From: LRRC superfamily expression in stromal cells predicts the clinical prognosis and platinum resistance of ovarian cancer

Fig. 6

GSEA for LRRC15. LRRC15 coexpressed genes in OC (LinkedOmics). The global LRRC15 highly correlated genes identified by Pearson’s test in the OC cohort (A). Heatmaps showing the top 50 genes positively and negatively correlated with LRRC15 in OC (B). Red indicates positively correlated genes, and blue indicates negatively correlated genes. Significantly enriched GO annotations (C) and KEGG pathways (D) of LRRC15 in the OC cohort. PPI network analysis was performed in GeneMANIA for the two gene signatures identified in GSE40266 and GSE40595. The results showed that LRR15 and LRRC32 were significantly correlated with the TGF-β pathway

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BMC Medical Genomics

ISSN: 1755-8794

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