Fig. 7

Relationship between LRRC15 expression and infiltration of immune cells. The EPIC method was used in TIMER2.0 for correlation analysis, and the results showed statistical significance A IHC slides were scanned at × 10 magnification on the PANNORAMIC SCAN III instrument (3DHISTECH) at a resolution of 0.25 μm/pixel. The figure shows the expression of LRRC15, PDPN and CD8 in platinum-resistant and platinum-sensitive patients B Spearman correlation analysis of LRRC115, PDPN and CD8. LRRC15 and PDPN were positively correlated (r = 0.56, p < 0.01). LRRC15 and CD8 were negatively correlated (r = −0.28, p = 0.13). CD8 and PDPN were negatively correlated (r = −0.38, p = 0.04) C The diagnostic ROC curve for LRRC15, PDPN and CD8 is an independent indicator D CD8 has certain accuracy (AUC = 0.865, CI = 0.736–0.994), PDPN has certain accuracy (AUC = 0.868, CI = 0.716–1.000), and LRRC15 has high accuracy (AUC = 0.920, CI = 0.825–1.000) in predicting drug resistance and sensitive outcomes. *The area under the ROC curve is between 0.5 and 1. The closer the AUC is to 1, the better the diagnostic effect. The lower the accuracy is when the AUC is 0.5–0.7, the certain the accuracy is when the AUC is 0.7–0.9, and the higher the accuracy is when the AUC is above 0.9