Three nervous system-specific expressed genes are potential biomarkers for the diagnosis of sporadic amyotrophic lateral sclerosis through a bioinformatic analysis

Table 4 Three SNPs shown the significant at p < 0.05 in the study

SNP	Group	Genotypes			Genotypes p value	Allele		Allele p value	OR (95%)
SNP	Group	GG	CG	CC		G	C	Allele p value	OR (95%)
rs463946	Cases (n = 30)	2	11	17	0.026	15 (25.0%)	45 (75.0%)	0.014	G:3.000 (1.164–7.732)
	Controls (n = 30)	1	3	26		5 (8.3%)	55 (91.7%)		C:0.818 (0.694–0.965)

SNP	Group	Genotypes			Genotypes p value	Allele		Allele p value	OR (95%)
SNP	Group	GG	AG	AA	Genotypes p value	G	A	Allele p value	OR (95%)
rs466433	Cases (n = 30)	2	11	17	0.026	15 (25.0%)	45 (75.0%)	0.014	G:3.000 (1.164–7.732)
	Controls (n = 30)	1	3	26		5 (8.3%)	55 (91.7%)		A:0.818 (0.694–0.965)

SNP	Group	Genotypes			Genotypes p value	Allele		Allele p value	OR (95%)
SNP	Group	GG	CC	CT		C	T	Allele p value	OR (95%)
rs364048	Cases (n = 30)	2	11	17	0.026	15 (25.0%)	45 (75.0%)	0.014	C:3.000 (1.164–7.732)
	Controls (n = 30)	1	3	26		5 (8.3%)	55 (91.7%)		T:0.818 (0.694–0.965)

ISSN: 1755-8794