Fig. 4
From: Relationship between drug targets and drug-signature networks: a network-based genome-wide landscape
Gene Ontology analysis of each gene set. Top 10 GO terms for A cellular component, B biological process, and C molecular function from each gene set. D Top 8 KEGG pathway terms from each gene set. Through KEGG pathway analysis (figure), it was revealed that drug-sensitive genes were involved in central dogma-related pathways such as the spliceosome, transcriptional regulation, and protein-processing progress. However, drug-target genes were involved in neural signaling pathways such as addiction to nitrogen, nicotine, and morphine, serotonergic synapses, and retrograde endocannabinoid signaling