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Table 2 Basic characteristics and allele frequencies among these SNPs

From: Variants in TPO rs2048722, PTCSC2 rs925489 and SEMA4G rs4919510 affect thyroid carcinoma susceptibility risk

SNP

Gene

Chr

Allele

MAF

HWE p–Value

OR (95% CI)

pb

Case

Control

rs2048722

TPO

2

A/G

0.489

0.460

0.583

1.12(0.92–1.36)

0.245

rs925489

PTCSC2

9

C/T

0.119

0.082

0.562

1.51(1.10–2.07)

0.011*

rs4919510

SEMA4G

10

C/G

0.447

0.468

0.368

0.92(0.76–1.11)

0.385

  1. HWE: Hardy–Weinberg equilibrium; MAF: minor allele frequency; SNP: single nucleotide polymorphism;
  2. Pb values calculated with two–sided χ2
  3. Bold type *pb < 0.05 indicates statistical significance
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BMC Medical Genomics

ISSN: 1755-8794

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