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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Screening of core genes prognostic for sepsis and construction of a ceRNA regulatory network

Fig. 3

GO annotation and GSEA functional clustering. (A) GO annotations for DEmRNAs from Biological Process (BP), Cellular Component (CC) and Molecular Function (MF). The colors from blue to red correspond to the q value from highest (blue) to lowest (red). The size of circles represents the number of genes enriched in the term. (B-C) GSEA functional clustering analysis. Upper part: Normalized enrichment score (NES), which indicates the enrichment of genes in a given gene set toward the up-regulated (positive NES, peak on the left) or down-regulated (negative NES, peak on the right) end of a pre-defined gene set correlated with phenotypes in sepsis; Middle part: Each gene of the gene set is represented by a vertical line and the lines (genes) before the peak belong to the leading edge subset and contribute to the most to the phenotype; Lower part: Gene list rank after normalization

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