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Table 3 Effects of genetically predicted RA on the risk of Asthma and AD in the MR analysis

From: Asthma and atopic dermatitis as risk factors for rheumatoid arthritis: a bidirectional mendelian randomization study

Exposure

Outcome

No. SNPs

MR methods

P

OR

95%CI

RA

Asthma

40

MR Egger

0.694

1.02

0.94–1.09

   

WM

0.396

1.01

0.98–1.05

   

IVW

0.673

1.01

0.98–1.03

   

Simple mode

0.258

1.04

0.97–1.12

   

Weighted mode

0.252

1.04

0.97–1.11

RA

AD

40

MR Egger

0.750

1.03

0.88–1.19

   

WM

0.249

1.05

0.97–1.14

   

IVW

0.342

1.03

0.97–1.09

   

Simple mode

0.533

1.06

0.88–1.29

   

Weighted mode

0.304

1.11

0.91–1.35

  1. MR, Mendelian randomization analysis; SNP, Single nucleotide polymorphism; IVW, Inverse variance weighted; WM, Weighted median; AD, Atopic dermatitis; RA, Rheumatoid arthritis
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BMC Medical Genomics

ISSN: 1755-8794

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