Carrier status | Carrier | Non carrier | ||||
---|---|---|---|---|---|---|
PRS strata | High | Intermediate | Low | High | Intermediate | Low |
Participants, n | 74 | 247 | 78 | 32,628 | 97,863 | 32,626 |
Cases, n (%) | 11 (14.86) | 16 (6.48) | 3 (3.85) | 686 (2.1) | 1004 (1.03) | 182 (0.56) |
Controls, n (%) | 63 (85.14) | 231 (93.52) | 75 (96.15) | 31,942 (97.9) | 96,859 (98.97) | 32,444 (99.44) |
Male, n (%) | 36 (48.65) | 110 (44.53) | 35 (44.87) | 14,824 (45.43) | 45,115 (46.1) | 14,876 (45.6) |
Female, n (%) | 38 (51.35) | 137 (55.47) | 43 (55.13) | 17,804 (54.57) | 52,748 (53.9) | 17,750 (54.4) |
Age at assessment, mean (SD) | 57.12 (8.89) | 56.16 (9.15) | 57.35 (8.42) | 56.93 (8.52) | 56.97 (8.51) | 56.96 (8.53) |
Family history of colorectal cancer, n (%) | 17 (22.97) | 53 (21.46) | 18 (23.08) | 4300 (13.18) | 10,671 (10.9) | 3005 (9.21) |