Inflammation and neuronal gene expression changes differ in early versus late chronic traumatic encephalopathy brain

Table 2 Common significant genes for CTE-L and CTE-H vs RHI from Fig. 2C

ENSG	Symbol	CTE-L			CTE-H
ENSG	Symbol	Mean	12fc	FDR	Mean	12fc	FDR
ENSG00000199805	RNU1-134P	15.59	− 1.65	0.10	18.08	− 1.44	0.03
ENSG00000130856	ZNF236	586.02	− 0.63	0.09	572.11	− 0.71	0.01
ENSG00000276975	HYDIN2	234.10	− 0.78	0.07	243.93	− 0.93	0.03
ENSG00000286021	AC112481.2	161.72	− 0.94	0.09	116.82	− 1.17	0.03
ENSG00000244625	MIATNB	79.93	− 0.60	0.09	69.15	− 0.57	0.10
ENSG00000233012	HDAC1P2	20.30	− 1.36	0.07	21.60	− 1.15	0.02
ENSG00000276002	RF00017	8.09	− 2.38	0.04	11.42	− 1.32	0.09
ENSG00000152208	GRID2	154.23	− 1.10	0.04	134.44	− 1.35	0.00
ENSG00000279557	AC010435.1	17.62	− 1.52	0.04	21.08	− 0.98	0.07
ENSG00000259706	HSP90B2P	71.62	− 1.19	0.09	92.97	− 1.28	0.05
ENSG00000110975	SYT10	55.42	− 1.28	0.09	47.40	− 1.75	0.00
ENSG00000140972	PDPK1	1789.15	− 0.54	0.09	1420.78	− 0.64	0.01
ENSG00000265010	AC087301.1	14.45	− 1.48	0.07	12.72	− 1.68	0.00
ENSG00000273136	NBPF26	398.68	− 1.36	0.04	493.63	− 1.20	0.07
ENSG00000236829	Z97634.1	120.46	− 1.06	0.09	125.60	− 0.89	0.06
ENSG00000100218	RSPH14	82.71	− 0.61	0.09	64.27	− 0.58	0.03
ENSG00000196141	SPATS2L	1798.83	− 0.54	0.09	1558.49	− 0.50	0.02
ENSG00000196290	NIF3L1	266.39	0.67	0.09	168.84	0.68	0.06

Genes were significant at FDR < 0.1 in both comparisons. Mean columns contain base mean count estimates for each gene (i.e. baseMean reported by DESeq2) l2fc columns contain log2 fold change estimates

ISSN: 1755-8794