Fig. 6

Identification of AFST related module and hub lncRNAs by WGCNA. A Heatmap of the correlation between the MEs and clinic traits. The Green module and the brown module are the most relevant modules with AFST. B Barplot of the MS across modules related to AFST. C Scatter plot between GS for AFST and the MM in brown module. D Scatter plot between GS for AFST and the MM in green module. E Scatter plot between GS for AFST and the MM in red module. F A Venn diagram of the lncRNAs identified in ceRNA network analysis and WGCNA. The overlap between lncRNAs in ceRNA network and lncRNAs with |GS|> 0.6 and |MM|> 0.5 in brown, green and red modules represent the hub lncRNAs for further validation. lncRNA, long non-coding RNA; AFST, atrial fibrillation related stroke; ME, module eigengene; MS, module significance; GS, gene significance; MM, module membership; ceRNA, competing endogenous RNA; WGCNA, weighted gene co-expression network analysis