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Fig. 7 | BMC Medical Genomics

Fig. 7

From: GAS6-AS1, a long noncoding RNA, functions as a key candidate gene in atrial fibrillation related stroke determined by ceRNA network analysis and WGCNA

Fig. 7

Construction of the AFST-related lncRNA-miRNA-mRNA sub-ceRNA network. Rhombuses represent lncRNAs, triangles represent miRNAs and ellipses represent mRNAs, respectively. Red and blue color represent down-regulation and up-regulation, respectively. According to ceRNA theory, lncRNAs are supposed to regulate mRNAs positively, so only the genes with the same color (red) in the network are in accordance with the theoretical expectation. ceRNA, competing endogenous RNA; AFST, atrial fibrillation related stroke; lncRNA, long non-coding RNA; miRNA, microRNA; mRNA, messenger RNA

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BMC Medical Genomics

ISSN: 1755-8794

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