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Fig. 10 | BMC Medical Genomics

Fig. 10

From: Identification of potential ferroptosis hub genes in acute-on-chronic liver failure based on bioinformatics analysis and experimental verification

Fig. 10

PSAT1 affects the serine synthesis pathway (SSP), TXNRD1 is involved in the cysteine depletion pathway, and HRAS indirectly inhibits ferroptosis through metabolic pathways and the xc-transporter. SQSTM1 may induce the Keap1/NRF2/NQO1 signaling pathway to protect against ferroptotic events in acute-on-chronic liver failure (ACLF)

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BMC Medical Genomics

ISSN: 1755-8794

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