Fig. 2

A Volcano map of DEGs in the ACLF group and control group. Two vertical lines indicate gene expression fold change (FC) > 2 and < − 2, respectively, and the horizontal line indicates the adjusted P value (FDR q-value) of 0.05. P values were calculated by two-sided Wilcoxon rank-sum test. The color of the dot represents the FDR (q-value) levels. B The first 50 DEGs are shown in the heatmap, with red representing significantly upregulated genes and blue representing significantly downregulated genes in the samples. C Venn diagram of ferroptosis-related DEGS. We intersected the ferroptosis dataset with GSE139602 to identify ferroptosis-related DEGs. Red indicates upregulation, and blue indicates downregulation