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Fig. 6 | BMC Medical Genomics

Fig. 6

From: Identification of potential ferroptosis hub genes in acute-on-chronic liver failure based on bioinformatics analysis and experimental verification

Fig. 6

Construction of the PPI network of ferroptosis-related DEGs and screening of hub genes. A The STRING database was used to construct the PPI network of ferroptosis-related DEGs, with nodes and edges. The darker the color and the wider the edge, the stronger the evidence for the interaction between proteins. B The node gene cluster with the highest score constructed by the MCODE plug-in in Cytoscape consists of 10 genes. C cytoHubba was used to construct the top 10 hub genes. The figure shows the top 10 hub genes constructed by the MCC method. D cytoHubba was used to predict the first stop node genes that interact with HRAS. A total of 23 genes were predicted

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BMC Medical Genomics

ISSN: 1755-8794

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