Table 3 List of top enriched KEGG pathways of ferroptosis-WGCNA genes

hsa04140

Autophagy - animal

6/14

141/8149

1.05E-05

2475/3091/10,533/9776/5599/5595

hsa04930

Type II diabetes mellitus

3/14

46/8149

1.58E-03

2475/5599/5595

hsa04012

ErbB signaling pathway

3/14

85/8149

4.40E-03

2475/5599/5595

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

3/14

89/8149

4.54E-03

2475/3091/5595

hsa04657

IL-17 signaling pathway

3/14

94/8149

5.00E-03

5599/7128/5595

hsa04066

HIF-1 signaling pathway

3/14

109/8149

6.85E-03

2475/3091/5595

hsa04668

TNF signaling pathway

3/14

112/8149

7.02E-03

5599/7128/5595

hsa04071

Sphingolipid signaling pathway

3/14

119/8149

7.58E-03

5599/4363/5595

hsa04068

FoxO signaling pathway

3/14

131/8149

9.14E-03

5599/472/5595

hsa04210

Apoptosis

3/14

136/8149

9.57E-03

5599/472/5595

hsa04910

Insulin signaling pathway

3/14

137/8149

9.57E-03

2475/5599/5595

hsa04150

mTOR signaling pathway

3/14

156/8149

1.24E-02

2475/23,175/5595

hsa04218

Cellular senescence

3/14

156/8149

1.24E-02

2475/472/5595

hsa05010

Alzheimer disease

4/14

384/8149

1.85E-02

2475/9776/5599/5595

hsa04621

NOD-like receptor signaling pathway

3/14

184/8149

1.85E-02

5599/7128/5595

hsa04613

Neutrophil extracellular trap formation

3/14

190/8149

1.96E-02

2475/10,533/5595

hsa05169

Epstein-Barr virus infection

3/14

202/8149

2.26E-02

960/5599/7128

hsa05208

Chemical carcinogenesis - reactive oxygen species

3/14

223/8149

2.57E-02

3091/5599/5595

hsa04920

Adipocytokine signaling pathway

2/14

69/8149

2.57E-02

2475/5599

hsa04137

Mitophagy - animal

2/14

72/8149

2.59E-02

3091/5599

hsa05022

Pathways of neurodegeneration - multiple diseases

4/14

476/8149

2.62E-02

2475/9776/5599/5595

hsa04658

Th1 and Th2 cell differentiation

2/14

92/8149

3.55E-02

5599/5595

hsa04933

AGE-RAGE signaling pathway in diabetic complications

2/14

100/8149

3.78E-02

5599/5595

hsa04064

NF-kappa B signaling pathway

2/14

104/8149

3.78E-02

7128/472

hsa04620

Toll-like receptor signaling pathway

2/14

104/8149

3.78E-02

5599/5595

hsa04660

T cell receptor signaling pathway

2/14

104/8149

3.78E-02

5599/5595

hsa05016

Huntington disease

3/14

306/8149

3.92E-02

2475/9776/5599

hsa04931

Insulin resistance

2/14

108/8149

3.92E-02

2475/5599

hsa04722

Neurotrophin signaling pathway

2/14

119/8149

4.53E-02

5599/5595