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Table 1 The characteristics of breast cancer cases and cancer-free controls

From: Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran

Characteristic a

Breast cancer

Control

P-value b

OR (95%CI)

Age

47.20 ± 10.41

45.88 ± 11.51

0.065

1.01 (0.99–1.02)

Age of menarche

13.05 ± 1.65

13.23 ± 1.56

0.116

1.07 (0.98–1.16)

Age of menopause c

47.79 ± 5.61

48.19 ± 5.21

0.545

1.01 (0.97–1.06)

Age of first gestation

21.39 ± 5.09

22.55 ± 4.53

0.001

1.05 (1.02–1.08)

BMI (Kg/m 2 ) d

27.66 ± 5.04

25.36 ± 4.36

< 0.001

1.11 (1.08–1.14)

BMI (Kg/m 2 )

BMI < 25

117 (28.4%)

260 (50.4%)

Reference

 

BMI ≥ 25

295 (71.6%)

256 (49.6%)

< 0.001

2.56 (1.94–3.37)

Menopause status

Pri & pre

238 (57.9%)

397 (74.8%)

Reference

 

Post

173 (42.1%)

134 (25.2%)

< 0.001

2.15 (1.63–2.84)

History of lactation

Negative

18 (4.7%)

20 (4.9%)

Reference

 

Positive

362 (95.3%)

390 (95.1%)

0.926

1.03 (0.54–1.98)

History of abortion

Negative

236 (64.1%)

281 (70.3%)

Reference

 

Positive

132 (35.9%)

119 (29.8%)

0.071

1.32 (0.98–1.79)

Physical activity

Negative

125 (42.4%)

51 (13.3%)

Reference

 

Positive

170 (57.6%)

332 (86.7%)

< 0.001

4.66 (3.20–6.80)

  1. a Data are presented as mean ± SD for continuous variable or number (percentage, %) for categorical variables;
  2. b Significant data has been shown in bold
  3. c The age of menopause in individuals with natural menopause
  4. d BMI: Body Mass Index