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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Confounding factors in profiling of locus-specific human endogenous retrovirus (HERV) transcript signatures in primary T cells using multi-study-derived datasets

Fig. 2

Sequencing parameter impact on HERV transcriptome mapping in primary CD4 + and CD8 + T cells. Raw mapped HERV and gene transcript counts are plotted and grouped by sequencing parameter read length (A), seqmode (B) and sequencing depth (C). (D) Correlation plot between sequencing depth (input read number) and the number of expressed HERV elements. A HERV element is considered to be expressed with at least one read being mapped to the HERV loci. (E) Correlation of dataset quality (i.e. the fraction of high quality mapped reads) versus the raw count of mapped HERV reads

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BMC Medical Genomics

ISSN: 1755-8794

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