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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Confounding factors in profiling of locus-specific human endogenous retrovirus (HERV) transcript signatures in primary T cells using multi-study-derived datasets

Fig. 3

Normalized read counts of CD4 + and CD8 + T cell derived HERV and gene transcripts without batch correction. (A) Principal component analysis based on HERV and gene transcripts. (B) Hierarchical cluster analysis and heatmap of HERV transcripts. Counts are log10 transformed, zero counts are depicted in grey and count matrix was sorted for deep sequenced dataset SRR644513 (CD4 + T cells, UWashington.HREMP) to increase clarity

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