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Fig. 11 | BMC Medical Genomics

Fig. 11

From: Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents

Fig. 11

Validation of the proposed KGs (receptors) and candidate drugs in favor of CRC by the literature review. A Validation of the proposed KGs: circles with green color indicate downregulated KGs, and pink color indicates up-regulated KGs, and each connected network with a circle indicates the reference in which the cKG is associated with CRC, B validation of the proposed candidate drugs: circles with green color indicate FDA approved and investigational drugs, purple color indicate investigational drugs and red color indicate unapproved drugs and each connected network with a circle indicates the references in which our suggested drugs might be effective against CRC treatment

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