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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Identifying potential biomarkers for the diagnosis and treatment of IgA nephropathy based on bioinformatics analysis

Fig. 4

GSEA analysis demonstrating most enriched gene sets between the healthy and IgAN group. (A) The most significant enriched gene set was proteasome pathway (ES = 0.666, NES = 1.782, p < 0.05). (B) The second significant enriched gene set was allograft rejection (ES = 0.707, NES = 1.586, p < 0.05). (C) The third significant enriched gene set was viral myocarditis (ES = 0.548, NES = 1.568, p < 0.05). (D) The fourth significant enriched gene set was graft versus host disease (ES = 0.685, NES = 1.568, p < 0.05). (E) The fifth significant enriched gene set was FCγR mediated phagocytosis (ES = 0.524, NES = 1.562, p < 0.05). (F) The sixth significant enriched gene set was natural killer cell mediated cytotoxicity. (ES = 0.543, NES = 1.534, p < 0.05). GSEA: gene set enrichment analysis; ES: enrichment score; NES: normalized enrichment score; IgAN: IgA nephropathy

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