Expression signature and molecular basis of CDH11 in OSCC detected by a combination of multiple methods

Wei, Yuxing; Cheng, Xujie; Deng, Limei; Dong, Hao; Wei, Huiping; Xie, Cheng; Tuo, Yangjuan; Li, Guangyu; Yu, Dahai; Cao, Yong

doi:10.1186/s12920-023-01499-7

BMC Medical Genomics

Table 2 Distribution of the proportions of different immune cells in OSCC patients with high or low CDH11 expression

From: Expression signature and molecular basis of CDH11 in OSCC detected by a combination of multiple methods

Types of immune cells	Subgroup	Proportions of immune cells in low or high CDH11 expression groups			t	P-value
Types of immune cells	Subgroup	Number	Mean	Standard deviation	t	P-value
B cells naive	CDH11 low expression group	170	0.025	0.035	2.045	0.042
B cells naive	CDH11 high expression group	171	0.034	0.046	2.045	0.042
B cells memory	CDH11 low expression group	170	0.003	0.010	-2.039	0.042
B cells memory	CDH11 high expression group	171	0.001	0.005	-2.039	0.042
T cells CD8	CDH11 low expression group	170	0.118	0.099	-4.661	< 0.001
T cells CD8	CDH11 high expression group	171	0.075	0.069	-4.661	< 0.001
T cells CD4 memory resting	CDH11 low expression group	170	0.098	0.079	4.681	< 0.001
T cells CD4 memory resting	CDH11 high expression group	171	0.138	0.076	4.681	< 0.001
T cells CD4 memory activated	CDH11 low expression group	170	0.065	0.053	-4.152	< 0.001
T cells CD4 memory activated	CDH11 high expression group	171	0.043	0.048	-4.152	< 0.001
T cells follicular helper	CDH11 low expression group	170	0.035	0.030	-2.919	0.004
T cells follicular helper	CDH11 high expression group	171	0.026	0.027	-2.919	0.004
NK cells activated	CDH11 low expression group	170	0.023	0.029	-4.492	< 0.001
NK cells activated	CDH11 high expression group	171	0.011	0.018	-4.492	< 0.001
Monocytes	CDH11 low expression group	170	0.004	0.013	-2.105	0.036
Monocytes	CDH11 high expression group	171	0.002	0.005	-2.105	0.036
Macrophages M0	CDH11 low expression group	170	0.215	0.148	3.283	0.001
Macrophages M0	CDH11 high expression group	171	0.269	0.159	3.283	0.001
Macrophages M2	CDH11 low expression group	170	0.093	0.051	2.111	0.035
Macrophages M2	CDH11 high expression group	171	0.106	0.060	2.111	0.035
Mast cells activated	CDH11 low expression group	170	0.020	0.035	2.333	0.02
Mast cells activated	CDH11 high expression group	171	0.031	0.050	2.333	0.02

Note: Only significant differential distribution (P < 0.05) was displayed in the Table

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ISSN: 1755-8794

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