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Table 2 Correlation between AVPR2 and relate genes and markers of immune cells analyzed by TIMER

From: AVPR2 is a potential prognostic biomarker and correlated with immune infiltration in head and neck squamous cell carcinoma

Description

Gene markers

None

Purity

Cor

P value

Cor

P value

Neutrophols

CCR7

0.523

***

0.502

***

ITGAM

0.362

***

0.327

***

CEACAM8

0.109

0.046

0.105

0.082

Natural killer cell

KIR3DL3

0.109

0.046

0.079

0.261

KIR2DS4

0.085

0.138

0.054

0.495

KIR3DL2

0.291

***

0.261

***

KIR3DL1

0.213

***

0.204

***

KIR2DL4

0.171

**

0.149

*

KIR2DL3

0.176

**

0.144

0.011

KIR2DL1

0.143

*

0.124

0.038

Monocyte

CSF1R

0.390

***

0.345

***

CD86

0.220

***

0.165

**

M1 Macrophage

NOS2

0.322

***

0.344

***

PTGS2

− 0.097

0.057

− 0.062

0.333

IRF5

0.237

***

0.224

***

M2 Macrophage

CD163

0.292

***

0.253

***

MS4A4A

0.284

***

0.232

***

VSIG4

0.269

***

0.223

***

TAM

CCL2

0.424

***

0.379

***

IL10

0.326

***

0.284

***

CD68

0.107

0.034

0.061

0.338

Dendritic cell

CD1C

0.450

***

0.403

***

HLA-DPB1

0.406

***

0.361

***

HLA-DPA1

0.362

***

0.314

***

HLA-DRA

0.347

***

0.297

***

ITGAX

0.328

***

0.289

***

HLA-DQB1

0.308

***

0.275

***

NRP1

0.220

***

0.178

**

B cell

CD19

0.504

***

0.484

***

CD79A

0.495

***

0.479

***

T cell (general)

CD3E

0.429

***

0.390

***

CD2

0.424

***

0.387

***

CD3D

0.396

***

0.353

***

CD8+ T cell

CD8B

0.365

***

0.331

***

CD8A

0.314

***

0.271

***

Th1

TBX21

0.358

***

0.322

***

STAT4

0.254

***

0.213

***

STAT1

0.061

0.243

0.017

0.828

IFNG

0.182

**

0.135

*

TNF

0.144

*

0.128

0.014

Th2

STAT5A

0.437

***

0.418

***

GATA3

0.273

***

0.245

***

IL13

0.237

***

0.210

***

STAT6

0.164

**

0.180

**

Th17

STAT3

0.257

***

0.240

***

IL17A

0.245

***

0.220

***

Treg

FOXP3

0.396

***

0.361

***

STAT5B

0.336

***

0.326

***

CCR8

0.338

***

0.304

***

TGFB1

− 0.103

0.043

− 0.119

0.026

Tfh

BCL6

0.278

***

0.325

***

IL21

0.296

***

0.260

***

T cell exhaustion

PDCD1

0.350

***

0.310

***

CTLA4

0.329

***

0.295

***

HAVCR2

0.286

***

0.239

***

LAG3

0.232

***

0.200

***

GZMB

0.212

***

0.170

**

  1. TAM, tumor-associated macrophage; Th, T helper cell; Tfh, Follicular helper T cell; Treg, regulatory T cell; Cor, R value of Spearman’s correlation; None, correlation without adjustment. Purity, correlation adjusted by purity
  2. *P < 0.01; **P < 0.001; ***P < 0.0001